New York, NY – [07/24/2024] – Microstructure Imaging, Inc. (MICSI) is excited to announce FDA 510k clearance for its MICSI-RMT software suite, which can be used for image enhancement in MRI images. MICSI-RMT employs the random matrix theory based “MP-PCA” algorithm to significantly improve MRI image quality through the redundancy of the MRI exam. Unlike traditional AI methods, MICSI-RMT achieves these remarkable results without the need for external training data or high-performance GPUs. Additionally, MICSI-RMT includes processing modules that support weighted linear least squares and Bayesian fitting techniques to facilitate quantitative analysis of diffusion weighted imaging. Lastly, MICSI-RMT features cutting edge DICOM data routing ensuring securing and seamless integration into medical workflows.
Key Insights from the Clinical Study:
- Improved Image Quality: In a randomized, blinded rater study, expert neuroradiologists assessed MRI images processed by MICSI-RMT and standard of care (SOC). The MICSI-RMT processed images were preferred for their clarity and reduced artifacts, achieving a mean Likert score of 3.7 compared to 2.8 for SOC images.
- Significant SNR Improvements: The software demonstrated notable enhancements in the signal-to-noise ratio (SNR), with MICSI-RMT showing improvements of up to 435.4% for diffusion MRI (dMRI) and 192.7% for functional MRI (fMRI).
- Precise Parametric Mapping: Modules for dMRI achieved notable reductions in standard deviation in parametric maps. Specifically, the standard deviation in Mean Diffusivity (MD) maps was reduced by over 56.3%.
For a detailed breakdown of the study methodologies, findings, and expert evaluations, please refer to our [comprehensive report]. (insert link)
A New Era in MRI Diagnostics
MICSI-RMT is a significant breakthrough as the first market solution designed to enhance the signal-to-noise ratio (SNR) for diffusion and functional MRI. Diffusion MRI involves the exponential signal suppression for contrast, often resulting in images with high noise levels. Similarly, the BOLD (Blood Oxygen Level Dependent) effect of functional MRI is only a few percent of the signal, which can easily be obscured by image noise. Despite the utility of these modalities in the clinical workflow, MICSI-RMT is the first product to directly address the noise problem.
Our enhancements are particularly transformative for neuroimaging applications where precise imaging is crucial. In stroke management, particularly over the posterior fossa, rapid and detailed imaging can guide timely and effective intervention strategies. In epilepsy monitoring and neurosurgical planning, the clarity and accuracy of images directly influence surgical decisions and outcomes. Our clinical study focused on critical improvements in these areas, enabling clinicians to make more informed decisions based on clearer, more precise imaging data.
This advancement not only boosts diagnostic accuracy but also sets a new standard in neurology care, positioning MICSI-RMT as an essential tool for medical imaging professionals.
Try MICSI-RMT for yourself and see how it can be integrated into your diagnostic workflow. For more information, to schedule a demonstration, or to discuss integration options, you can contact us below.